Developing ASIC1-targeted therapeutics for ischemic injury
Advancing differentiated peptide, small-molecule, and formulation-based programmes enabled by FRDTFrom mechanism to therapeutic programmes
Approach
From ASIC1 biology to a differentiated multi-asset pipeline enabled by FRDT
Why YATREX
Mechanism
Targeting ASIC1-mediated injury pathways with strong translational rationale.A multi-modal pipeline spanning polycyclic peptides, formulation-enabled repurposing, and small molecules.
Differentation
Execution
Preclinical programmes supported by defined pharmacokinetic and efficacy development plans.
YATRX-111 — Polycyclic peptide (Preclinical)YATRX-203 — Formulation-enabled repurposing programme (Preclinical)YATRX-305 — Optimised small-molecule programme (Preclinical)